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Breakthrough In Malaria Vaccine Reported

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Breakthrough In Malaria Vaccine Reported

Post by SKOOKID on Fri Aug 09, 2013 4:16 pm

An experimental malaria vaccine called PfSPZ is
showing promise after it was found to have
blocked the disease in early clinical trials, according
to a new study published by Science magazine on

Researchers are calling the vaccine a breakthrough
while also cautioning that PfSPZ isn't ready for
prime time just yet.

The vaccine, which is made using a weakened form
of the disease, was administered in varying doses
to a group of more than three dozen volunteers.
Six people, each of whom were given a full five
doses of the vaccine, were unable to contract
malaria when exposed to the disease, the study

This is the first time any vaccine has achieved 100%
effectiveness in any trial, researchers report.
Nine others were given four doses of PfSPZ, three
of whom became infected in the trial.
Of another 12 who took part in the trial but weren't
given the vaccine, 11 contracted malaria, the study

The trial — which included testing handled by the
National Institutes of Health, the US Army, and the
US Navy — is a first step in figuring out just how
safe and effective the vaccine might be.

For one thing, PfSPZ needs to be tested on a
greater number of people, and researchers aren't
sure as of yet how long the vaccine will be effective

The vaccine is also only currently available by way
of intravenous injection (IV), which makes it more
difficult to get to people than a shot or a pill.

Huge potential, But Questions Remain
Still, Stephen Hoffman, the CEO of the biotech
company that developed PfSPZ, is hopeful.

"We have demonstrated for the first time in the
history of malaria that one can completely protect
individuals against malaria infected mosquitos," he
told NPR.

According to CNN, Malaria infects more than 200
million people each year, and it claimed the lives of
660,000 in 2010.

The disease is particularly rampant in developing
nations. From here, Hoffman's company, Sanaria,
will test out the vaccine in larger trials in Tanzania
and other parts of Africa, NPR said.

If all goes well, the earliest PfSPZ could make it to
market would be late 2017 or early 2018, Hoffman


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Join date : 2013-07-15
Location : Kaduna , Nigeria

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